Anatomy & Physiology

Anatomy & Physiology Study Guide • The effect of a presynaptic neuron's activation on a postsynaptic neuron may be altered by other neurons. • The greater the degree of sustained depolarization at the axon hillock, the higher the frequency of generation of action potentials. At a frequency of about 1000 per second, the relative refractory period has been eliminated, and further depolarization will have no effect.

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