Anatomy & Physiology

Anatomy & Physiology Study Guide

The Spleen The largest collection of lymphoid tissue in the body is within the adult spleen. In essence, the spleen performs the same functions for blood that lymph nodes perform for lymph. Functions of the spleen are the removal of abnormal blood cells and other blood components by phagocytosis, the storage of iron recycled from red blood cells, and the initiation of immune responses by T cells and B cells in response to antigens in circulating blood. Splenic blood vessels and lymphatic vessels communicate with the spleen on the visceral surface at the hilum .

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